Our Clinical Trials for Brain Tumors

Here you can find a continually updated listing of Memorial Sloan-Kettering's current clinical trials for cancers of the brain and spinal cord. Trials are listed according to the type of tumor. To learn more about a study, choose from the list below.

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Gliomas
Primary Central Nervous System (CNS) Lymphoma
Brain Metastases
Other Trials
Pediatric Brain Tumors

Gliomas

A Pharmacokinetic and Phase II Study of Sunitinib Malate in Recurrent Malignant Gliomas
Abrey, Lauren, MD

[Protocol 07-153]
A Phase I Study of Vorinostat (Suberoylanilide Hydroxamic Acid, or SAHA) in Combination with Temozolomide in Patients with Malignant Gliomas
Lassman, Andrew, MD

[Protocol 06-029]
A Phase I Study of XL765 in Combination with Temozolomide in Patients with Malignant Gliomas
Omuro, Antonio, MD

[Protocol 08-057]
A Phase II Trial of Continuous Low-Dose Temozolomide for Patients with Recurrent Malignant Glioma
Abrey, Lauren, MD

[Protocol 07-064]
A Phase II Trial of Intensive Chemotherapy & Autotransplantation in Patients with Newly Diagnosed Anaplastic Oligodendroglioma
Abrey, Lauren, MD

[Protocol 02-089]
A Phase II Trial of Temozolomide and Radiotherapy Followed by Temozolomide and Maintenance Cis-retinoic Acid for Patients with Newly Diagnosed Gliomas
Abrey, Lauren, MD

[Protocol 05-079]
Phase I Study of Aflibercept With or After Radiation Therapy and Temozolomide in Patients with Malignant Glioma
Lassman, Andrew, MD

[Protocol 08-106]
Phase I/II Study of BAY 43-9006 (Sorafenib) in Combination with Several Other Drugs in Patients with Gliomas
Lassman, Andrew, MD

[Protocol 06-109]

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Primary Central Nervous System (CNS) Lymphoma

A Phase II Study of Rituximab and Temozolomide in Recurrent Primary CNS Lymphoma
Abrey, Lauren, MD

[Protocol 05-119]
A Phase II Study of Rituximab, Methotrexate, Procarbazine and Vincristine Followed by High-Dose Chemotherapy with Autologous Stem Cell Rescue in Newly Diagnosed Primary CNS Lymphoma
Abrey, Lauren, MD

[Protocol 04-129]
A Pilot Study of Combined Immunochemotherapy Followed by Reduced Dose Radiotherapy for Patients with Newly Diagnosed Primary Central Nervous System Lymphoma
Abrey, Lauren, MD

[Protocol 01-146]

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Brain Metastases

A Phase II Study of Intrathecal I¹³¹-3F8 in Patients with GD2-Expressing Central Nervous System and Leptomeningeal Neoplasms
Kramer, Kim, MD

[Protocol 05-122]
Phase II Study of Patupilone (EPO906) to Treat Recurrent or Progressive Brain Metastases in Patients with Non-Small Cell Lung Cancer
Abrey, Lauren, MD

[Protocol 05-085]

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Other Trials

A Phase II Trial of Sunitinib (Sutent^®) in Patients with Recurrent or Inoperable Meningioma
Abrey, Lauren, MD

[Protocol 07-135]
Adjunctive Donepezil Therapy and Genetic Risk Factors of Cognitive Dysfunction in Brain Tumor Survivors
Correa, Denise, PhD

[Protocol 04-122]
GLIOGENE: Genetic Epidemiology of Glioma International Consortium
Bernstein, Jonine, PhD

[Protocol 07-137]
Reorganization of Language Function in Patients with Brain Tumors
Holodny, Andrei, MD

[Protocol 05-043]

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Pediatric Brain Tumors

A Phase I Study of Intrathecal Radioimmunotherapy Using ¹³¹I-8H9 for Central Nervous System/Leptomeningeal Cancers
Kramer, Kim, MD

[Protocol 03-133]
A Phase II Study of Conformal Radiotherapy in Patients with Low-Grade Gliomas
Dunkel, Ira, MD

[Protocol 07-049]
A Phase II Study of Intrathecal I¹³¹-3F8 in Patients with GD2-Expressing Central Nervous System and Leptomeningeal Neoplasms
Kramer, Kim, MD

[Protocol 05-122]
A Phase II Study of Motexafin-Gadolinium and Involved Field Radiation Therapy for Intrinsic Pontine Glioma of Childhood
Dunkel, Ira, MD

[Protocol 07-140]
A Phase III Study Assessing Carboplatin and/or Isotretinoin plus Radiation in Patients with Supratentorial Primitive Neuroectodermal Tumor or High-Risk Medulloblastoma
Gilheeney, Stephen, MD

[Protocol 07-174]
A Phase III Study of Intensive Induction Chemotherapy with or without Methotrexate Followed by Consolidation Therapy with Stem Cell Rescue in Young Children Newly Diagnosed with Supratentorial PNET or High-Risk Medulloblastoma
Gilheeney, Stephen, MD

[Protocol 07-170]
Phase I Study of Single Agent Perifosine for Recurrent Pediatric Solid Tumors
Becher, Oren, MD

[Protocol 08-091]
Phase II Study of Nimotuzumab (TheraCIM^®) in Pediatric Patients with Recurrent Diffuse Intrinsic Pontine Glioma
Trippett, Tanya, MD

[Protocol 08-034]
Radioimmunotherapy, Reduced-Dose External Beam Craniospinal Radiation Therapy with IMRT Boost & Chemotherapy for Patients with Standard-Risk Medulloblastoma
Dunkel, Ira, MD

[Protocol 02-088]
Radiotherapy Alone versus Chemotherapy Followed by Response-Based Radiotherapy for Newly Diagnosed Primary CNS Germinoma
Dunkel, Ira, MD

[Protocol 07-167]

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